The cytokine-activated tyrosine kinase JAK2 activates Raf-1 in a p21ras-dependent manner.

JAK2, a member of the Janus kinase superfamily was found to interact functionally with Raf-1, a central component of the ras/mitogen-activated protein kinase signal transduction pathway. Interferon-gamma and several other cytokines that are known to activate JAK2 kinase were also found to stimulate...

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Bibliografiske detaljer
Main Authors: Xia, K, Mukhopadhyay, N K, Inhorn, R C, Barber, D L, Rose, P E, Lee, R S, Narsimhan, R P, D'Andrea, A D, Griffin, J D, Roberts, T M
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC38118/
https://ncbi.nlm.nih.gov/pubmed/8876196
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