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The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site.

The Raf-1 protein kinase is the best-characterized downstream effector of activated Ras. Interaction with Ras leads to Raf-1 activation and results in transduction of cell growth and differentiation signals. The details of Raf-1 activation are unclear, but our characterization of a second Ras-bindin...

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Autori principali: Mott, H R, Carpenter, J W, Zhong, S, Ghosh, S, Bell, R M, Campbell, S L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC38667/
https://ncbi.nlm.nih.gov/pubmed/8710867
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