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The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site.

The Raf-1 protein kinase is the best-characterized downstream effector of activated Ras. Interaction with Ras leads to Raf-1 activation and results in transduction of cell growth and differentiation signals. The details of Raf-1 activation are unclear, but our characterization of a second Ras-bindin...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Mott, H R, Carpenter, J W, Zhong, S, Ghosh, S, Bell, R M, Campbell, S L
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38667/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8710867/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.16.8312
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