The cytokine-activated tyrosine kinase JAK2 activates Raf-1 in a p21ras-dependent manner.

JAK2, a member of the Janus kinase superfamily was found to interact functionally with Raf-1, a central component of the ras/mitogen-activated protein kinase signal transduction pathway. Interferon-gamma and several other cytokines that are known to activate JAK2 kinase were also found to stimulate...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Xia, K, Mukhopadhyay, N K, Inhorn, R C, Barber, D L, Rose, P E, Lee, R S, Narsimhan, R P, D'Andrea, A D, Griffin, J D, Roberts, T M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38118/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8876196/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.21.11681
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