The cytokine-activated tyrosine kinase JAK2 activates Raf-1 in a p21ras-dependent manner.
JAK2, a member of the Janus kinase superfamily was found to interact functionally with Raf-1, a central component of the ras/mitogen-activated protein kinase signal transduction pathway. Interferon-gamma and several other cytokines that are known to activate JAK2 kinase were also found to stimulate...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38118/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8876196/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.21.11681 |
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