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N-Cinnamoylated Aminoquinolines as Promising Antileishmanial Agents

A series of cinnamic acid conjugates of primaquine and chloroquine were evaluated for their in vitro antileishmanial activities. Although primaquine derivatives had modest activity, chloroquine conjugates exhibited potent activity against both promastigotes (50% inhibitory concentration [IC(50)] = 2...

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Detalhes bibliográficos
Main Authors: Vale-Costa, S., Costa-Gouveia, J., Pérez, B., Silva, T., Teixeira, C., Gomes, P., Gomes, M. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811464/
https://ncbi.nlm.nih.gov/pubmed/23917315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00557-13
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