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Antileishmanial Activity of the Antiulcer Agent Omeprazole

The benzimidazole compound omeprazole, used widely for the treatment of peptic ulcer disease, inhibits the growth of Leishmania donovani, the causative agent of visceral leishmaniasis. Promastigotes cultured at acidic pH and amastigotes within infected macrophages are reduced 90% or more with 150 μM...

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Autori principali: Jiang, Suping, Meadows, Juliana, Anderson, Steven A., Mukkada, Antony J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC127324/
https://ncbi.nlm.nih.gov/pubmed/12121934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.8.2569-2574.2002
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