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Antileishmanial Activity of the Antiulcer Agent Omeprazole

The benzimidazole compound omeprazole, used widely for the treatment of peptic ulcer disease, inhibits the growth of Leishmania donovani, the causative agent of visceral leishmaniasis. Promastigotes cultured at acidic pH and amastigotes within infected macrophages are reduced 90% or more with 150 μM...

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書誌詳細
主要な著者: Jiang, Suping, Meadows, Juliana, Anderson, Steven A., Mukkada, Antony J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC127324/
https://ncbi.nlm.nih.gov/pubmed/12121934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.8.2569-2574.2002
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