N-Cinnamoylated Aminoquinolines as Promising Antileishmanial Agents

A series of cinnamic acid conjugates of primaquine and chloroquine were evaluated for their in vitro antileishmanial activities. Although primaquine derivatives had modest activity, chloroquine conjugates exhibited potent activity against both promastigotes (50% inhibitory concentration [IC(50)] = 2...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vale-Costa, S., Costa-Gouveia, J., Pérez, B., Silva, T., Teixeira, C., Gomes, P., Gomes, M. S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2013
Pynciau:
Susceptibility
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811464/
https://ncbi.nlm.nih.gov/pubmed/23917315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00557-13
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