N-Cinnamoylated Aminoquinolines as Promising Antileishmanial Agents

A series of cinnamic acid conjugates of primaquine and chloroquine were evaluated for their in vitro antileishmanial activities. Although primaquine derivatives had modest activity, chloroquine conjugates exhibited potent activity against both promastigotes (50% inhibitory concentration [IC(50)] = 2...

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Autors principals: Vale-Costa, S., Costa-Gouveia, J., Pérez, B., Silva, T., Teixeira, C., Gomes, P., Gomes, M. S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Susceptibility
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811464/
https://ncbi.nlm.nih.gov/pubmed/23917315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00557-13
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