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Antileishmanial and Antitrypanosomal Activities of the 8-Aminoquinoline Tafenoquine
The 8-aminoquinoline tafenoquine showed significant in vitro activity against Leishmania species, including L. donovani amastigotes in macrophages, with 50% inhibitory concentrations (IC(50)s) between 0.1 and 4.0 μM for both pentavalent antimony (SbV)-sensitive and SbV-resistant strains and by oral...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2981226/ https://ncbi.nlm.nih.gov/pubmed/20837750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00985-10 |
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