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Antileishmanial and Antitrypanosomal Activities of the 8-Aminoquinoline Tafenoquine

The 8-aminoquinoline tafenoquine showed significant in vitro activity against Leishmania species, including L. donovani amastigotes in macrophages, with 50% inhibitory concentrations (IC(50)s) between 0.1 and 4.0 μM for both pentavalent antimony (SbV)-sensitive and SbV-resistant strains and by oral...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yardley, Vanessa, Gamarro, Francisco, Croft, Simon L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981226/
https://ncbi.nlm.nih.gov/pubmed/20837750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00985-10
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