Lack of Pharmacokinetic Interaction between Rilpivirine and Integrase Inhibitors Dolutegravir and GSK1265744

Dolutegravir (DTG) and GSK1265744 are HIV integrase inhibitors (INIs) in clinical development. The oral formulation of rilpivirine (RPV), a nonnucleoside reverse transcriptase inhibitor (NNRTI), has been approved for treatment-naive HIV infection. Long-acting depot injections of GSK1265744 and RPV a...

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Détails bibliographiques
Auteurs principaux: Ford, Susan L., Gould, Elizabeth, Chen, Shuguang, Margolis, David, Spreen, William, Crauwels, Herta, Piscitelli, Stephen
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811315/
https://ncbi.nlm.nih.gov/pubmed/23979733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01235-13
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