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Effect of Prednisone on the Pharmacokinetics of the Integrase Inhibitor Dolutegravir

Prednisone, a corticosteroid frequently used to treat common AIDS-related illnesses and comorbidities, has been shown to induce drug metabolism. This study was performed to determine whether prednisone coadministration affected the pharmacokinetics of dolutegravir (DTG). In this open-label, repeat-d...

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Detalhes bibliográficos
Main Authors: Song, Ivy H., Borland, Julie, Chen, Shuguang, Savina, Paul, Peppercorn, Amanda F., Piscitelli, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754328/
https://ncbi.nlm.nih.gov/pubmed/23817375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00728-13
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