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Effect of Fosamprenavir-Ritonavir on the Pharmacokinetics of Dolutegravir in Healthy Subjects

Dolutegravir (DTG) is an HIV integrase inhibitor (INI) with demonstrated activity in INI-naive and INI-resistant patients. The objective of this open-label, 2-period, single-sequence study was to evaluate the effect of fosamprenavir-ritonavir (FPV-RTV) on the steady-state plasma pharmacokinetics of...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Song, Ivy, Borland, Julie, Chen, Shuguang, Peppercorn, Amanda, Wajima, Toshihiro, Piscitelli, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249430/
https://ncbi.nlm.nih.gov/pubmed/25155604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03282-14
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