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Pharmacokinetic Interaction between Fosamprenavir-Ritonavir and Rifabutin in Healthy Subjects

Rifabutin (RFB) is administered for treatment of tuberculosis and Mycobacterium avium complex infection, including use for patients coinfected with human immunodeficiency virus (HIV). Increased systemic exposure to RFB and its equipotent active metabolite, 25-O-desacetyl-RFB (dAc-RFB), has been repo...

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Bibliographic Details
Main Authors: Ford, Susan L., Chen, Ya-Chi, Lou, Yu, Borland, Julie, Min, Sherene S., Yuen, Geoffrey J., Shelton, Mark J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224730/
https://ncbi.nlm.nih.gov/pubmed/18056271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00724-07
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