Pharmacokinetics of Darunavir/Ritonavir and Rifabutin Coadministered in HIV-Negative Healthy Volunteers

The drug-drug interaction between rifabutin (RFB) and darunavir/ritonavir (DRV/r) was examined in a randomized, three-way crossover study of HIV-negative healthy volunteers who received DRV/r 600/100 mg twice a day (BID) (treatment A), RFB 300 mg once a day (QD) (treatment B), and DRV/r 600/100 mg B...

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Autori principali: Sekar, Vanitha, Lavreys, Ludo, Van de Casteele, Tom, Berckmans, Cindy, Spinosa-Guzman, Sabrina, Vangeneugden, Tony, De Pauw, Martine, Hoetelmans, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
Soggetti:
Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944603/
https://ncbi.nlm.nih.gov/pubmed/20660678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01749-09
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