Pharmacokinetics of darunavir/ritonavir and ketoconazole following co-administration in HIV–healthy volunteers

AIMS: To investigate the interaction between ketoconazole and darunavir (alone and in combination with low-dose ritonavir), in HIV–healthy volunteers. METHODS: Volunteers received darunavir 400 mg bid and darunavir 400 mg bid plus ketoconazole 200 mg bid, in two sessions (Panel 1), or darunavir/rito...

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Detalhes bibliográficos
Main Authors: Sekar, Vanitha J, Lefebvre, Eric, De Pauw, Martine, Vangeneugden, Tony, Hoetelmans, Richard M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Drug Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492919/
https://ncbi.nlm.nih.gov/pubmed/18460033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03191.x
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