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Role of the IgH Intronic Enhancer Eμ in Clonal Selection at the Pre-B to Immature B Cell Transition()

We previously described a check-point for allelic exclusion that occurs at the pre-B to immature B cell transition and is dependent upon IgH intronic enhancer, Eμ. We now provide evidence that the breach in allelic exclusion associated with Eμ deletion results from decreased Igμ levels that make it...

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Detalhes bibliográficos
Main Authors: Peng, Cheng, Eckhardt, Laurel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810302/
https://ncbi.nlm.nih.gov/pubmed/24058175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301858
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