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In a Model of Immunoglobulin Heavy-Chain (IGH)/MYC Translocation, the Igh 3′ Regulatory Region Induces MYC Expression at the Immature Stage of B Cell Development
Reciprocal translocations involving the immunoglobulin loci and the cellular oncogene MYC are hallmark mutations of the human postgerminal center B cell neoplasm, Burkitt’s lymphoma. They are occasionally found in other B cell lymphomas, as well. Translocations involving the heavy chain locus (IGH)...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742353/ https://ncbi.nlm.nih.gov/pubmed/17639584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20480 |
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