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Genetic reporter system for oncogenic Igh–Myc translocations in mice

The Myc-deregulating chromosomal T(12;15)(Igh–Myc) translocation, the hallmark mutation of inflammation- and interleukin 6-dependent mouse plasmacytoma (PCT), is the premier model of cancer-associated chromosomal translocations because it is the only translocation in mice that occurs spontaneously (...

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Détails bibliographiques
Auteurs principaux: Takizawa, M, Kim, JS, Tessarollo, L, McNeil, N, Waldschmidt, TJ, Casellas, R, Ried, T, Janz, S
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108853/
https://ncbi.nlm.nih.gov/pubmed/20453890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.150
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