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In a Model of Immunoglobulin Heavy-Chain (IGH)/MYC Translocation, the Igh 3′ Regulatory Region Induces MYC Expression at the Immature Stage of B Cell Development

Reciprocal translocations involving the immunoglobulin loci and the cellular oncogene MYC are hallmark mutations of the human postgerminal center B cell neoplasm, Burkitt’s lymphoma. They are occasionally found in other B cell lymphomas, as well. Translocations involving the heavy chain locus (IGH)...

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Hlavní autoři: Yan, Yi, Park, Sung Sup, Janz, Siegfried, Eckhardt, Laurel A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742353/
https://ncbi.nlm.nih.gov/pubmed/17639584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20480
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