Yüklüyor......
A role for the IgH intronic enhancer Eμ in enforcing allelic exclusion
The intronic enhancer (Eμ) of the immunoglobulin heavy chain (IgH) locus is critical for V region gene assembly. To determine Eμ's subsequent functions, we created an Igh allele with assembled V(H) gene but with Eμ removed. In mice homozygous for this Eμ-deficient allele, B cell development was...
Kaydedildi:
| Asıl Yazarlar: | , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Rockefeller University Press
2009
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2626684/ https://ncbi.nlm.nih.gov/pubmed/19114667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081202 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|