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Role of the IgH Intronic Enhancer Eμ in Clonal Selection at the Pre-B to Immature B Cell Transition()

We previously described a check-point for allelic exclusion that occurs at the pre-B to immature B cell transition and is dependent upon IgH intronic enhancer, Eμ. We now provide evidence that the breach in allelic exclusion associated with Eμ deletion results from decreased Igμ levels that make it...

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Hlavní autoři: Peng, Cheng, Eckhardt, Laurel A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810302/
https://ncbi.nlm.nih.gov/pubmed/24058175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301858
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