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Elucidation of IgH intronic enhancer functions via germ-line deletion
Studies of chimeric mice demonstrated that the core Ig heavy chain (IgH) intronic enhancer (iEμ) functions in V(D)J and class switch recombination at the IgH locus. To more fully evaluate the role of this element in these and other processes, we generated mice homozygous for germ-line mutations in w...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2005
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1242331/ https://ncbi.nlm.nih.gov/pubmed/16186486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507090102 |
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