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Elucidation of IgH intronic enhancer functions via germ-line deletion
Studies of chimeric mice demonstrated that the core Ig heavy chain (IgH) intronic enhancer (iEμ) functions in V(D)J and class switch recombination at the IgH locus. To more fully evaluate the role of this element in these and other processes, we generated mice homozygous for germ-line mutations in w...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2005
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1242331/ https://ncbi.nlm.nih.gov/pubmed/16186486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507090102 |
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