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Transcription of productive and nonproductive VDJ-recombined alleles after IgH allelic exclusion
The process of allelic exclusion ensures that each B cell expresses a B-cell receptor encoded by only one of its Ig heavy (IgH) and light (IgL) chain alleles. Although its precise mechanism is unknown, recruitment of the nonfunctional IgH allele to centromeric heterochromatin correlates with the est...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2230841/ https://ncbi.nlm.nih.gov/pubmed/17805345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601846 |
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