Cellular Influx, Efflux, and Anabolism of 3-Carboranyl Thymidine Analogs: Potential Boron Delivery Agents for Neutron Capture Therapy

3-[5-{2-(2,3-Dihydroxyprop-1-yl)-o-carboran-1-yl}pentan-1-yl]thymidine (N5-2OH) is a first generation 3-carboranyl thymidine analog (3CTA) that has been intensively studied as a boron-10 ((10)B) delivery agent for neutron capture therapy (NCT). N5-2OH is an excellent substrate of thymidine kinase 1...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sjuvarsson, Elena, Damaraju, Vijaya L., Mowles, Delores, Sawyer, Michael B., Tiwari, Rohit, Agarwal, Hitesh K., Khalil, Ahmed, Hasabelnaby, Sherifa, Goudah, Ayman, Nakkula, Robin J., Barth, Rolf F., Cass, Carol E., Eriksson, Staffan, Tjarks, Werner
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Metabolism, Transport, and Pharmacogenomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807065/
https://ncbi.nlm.nih.gov/pubmed/24006340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.207464
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados