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Synthesis, biological evaluation, and radioiodination of halogenated closo-carboranyl thymidine analogues(1)

The synthesis and initial biological evaluation of 3-carboranyl thymidine analogues (3CTAs) that are (radio)halogenated at the closo-carborane cluster is described. Radiohalogenated 3CTAs have the potential to be used in the radiotherapy and imaging of cancer, as they may be selectively entrapped in...

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Detalhes bibliográficos
Main Authors: Tiwari, Rohit, Toppino, Antonio, Agarwal, Hitesh K., Huo, Tianyao, Byun, Youngjoo, Gallucci, Judith, Hasabelnaby, Sherifa, Khalil, Ahmed, Goudah, Ayman, Baiocchi, Robert A., Darby, Michael V., Barth, Rolf. F., Tjarks, Werner
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257809/
https://ncbi.nlm.nih.gov/pubmed/22175713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic202150b
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