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Structure and Function of the Reduced Folate Carrier: A Paradigm of A Major Facilitator Superfamily Mammalian Nutrient Transporter

Folates are essential for life and folate deficiency contributes to a host of health problems including cardiovascular disease, fetal abnormalities, neurologic disorders, and cancer. Antifolates, represented by methotrexate, continue to occupy a unique niche among the modern day pharmacopoeia for ca...

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Bibliografski detalji
Glavni autori: Matherly, Larry H., Hou, Zhanjun
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806226/
https://ncbi.nlm.nih.gov/pubmed/18804694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0083-6729(08)00405-6
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