Development and Validation of Chemical Features-Based Proton-Coupled Folate Transporter/Activity and Reduced Folate Carrier/Activity Models (Pharmacophores)

Documenti analoghi

• The promise and challenges of exploiting the proton-coupled folate transporter for selective therapeutic targeting of cancer
  di: Matherly, Larry H., et al.
  Pubblicazione: (2017)
• The human proton-coupled folate transporter: Biology and therapeutic applications to cancer
  di: Desmoulin, Sita Kugel, et al.
  Pubblicazione: (2012)
• Functional Loss of the Reduced Folate Carrier Enhances the Antitumor Activities of Novel Antifolates with Selective Uptake by the Proton-Coupled Folate Transporter
  di: Desmoulin, Sita Kugel, et al.
  Pubblicazione: (2012)
• Synthesis and biological activity of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl regioisomers as inhibitors of de novo purine biosynthesis with selectivity for cellular uptake by high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier
  di: Wang, Lei, et al.
  Pubblicazione: (2012)
• Synthesis and biological activity of a novel series of 6-substituted thieno[2,3-d]pyrimidine antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors over the reduced folate carrier and proton-coupled folate transporter for cellular entry
  di: Deng, Yijun, et al.
  Pubblicazione: (2009)