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Post-transcriptional regulation of the human reduced folate carrier as a novel adaptive mechanism in response to folate excess or deficiency

The RFC (reduced folate carrier) is the principal mechanism by which folates and clinically used antifolates are delivered to mammalian cells. hRFC (human RFC) is subject to complex transcriptional controls and exists as homo-oligomer. To explore the post-transcriptional regulation of hRFC by exogen...

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Bibliografische gegevens
Hoofdauteurs: Hou, Zhanjun, Orr, Steve, Matherly, Larry H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Portland Press Ltd. 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122975/
https://ncbi.nlm.nih.gov/pubmed/24949876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20140065
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