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Oligomeric Structure of the Human Reduced Folate Carrier: IDENTIFICATION OF HOMO-OLIGOMERS AND DOMINANT-NEGATIVE EFFECTS ON CARRIER EXPRESSION AND FUNCTION

The ubiquitously expressed reduced folate carrier (RFC) is the major transport system for folate cofactors in mammalian cells and tissues. Previous considerations of RFC structure and mechanism were based on the notion that RFC monomers were sufficient to mediate transport of folate and antifolate s...

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Main Authors: Hou, Zhanjun, Matherly, Larry H.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631974/
https://ncbi.nlm.nih.gov/pubmed/19019821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807206200
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