Identification and Functional Impact of Homo-oligomers of the Human Proton-coupled Folate Transporter

The proton-coupled folate transporter (PCFT; SLC46A1) is a proton-folate symporter that is abundantly expressed in solid tumors and normal tissues, such as duodenum. The acidic pH optimum for PCFT is relevant to intestinal absorption of folates and could afford a means of selectively targeting tumor...

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Detalhes bibliográficos
Main Authors: Hou, Zhanjun, Kugel Desmoulin, Sita, Etnyre, Erika, Olive, Mary, Hsiung, Benjamin, Cherian, Christina, Wloszczynski, Patrick A., Moin, Kamiar, Matherly, Larry H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281668/
https://ncbi.nlm.nih.gov/pubmed/22179615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.306860
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