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Identification and Functional Impact of Homo-oligomers of the Human Proton-coupled Folate Transporter
The proton-coupled folate transporter (PCFT; SLC46A1) is a proton-folate symporter that is abundantly expressed in solid tumors and normal tissues, such as duodenum. The acidic pH optimum for PCFT is relevant to intestinal absorption of folates and could afford a means of selectively targeting tumor...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3281668/ https://ncbi.nlm.nih.gov/pubmed/22179615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.306860 |
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