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Kindlin-3 regulates integrin activation and adhesion reinforcement of effector T cells

Activated T cells use very late antigen-4/α4β1 integrin for capture, rolling on, and firm adhesion to endothelial cells, and use leukocyte function-associated antigen-1/αLβ2 integrin for subsequent crawling and extravasation. Inhibition of α4β1 is sufficient to prevent extravasation of activated T c...

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Библиографические подробности
Главные авторы: Moretti, Federico A., Moser, Markus, Lyck, Ruth, Abadier, Michael, Ruppert, Raphael, Engelhardt, Britta, Fässler, Reinhard
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801036/
https://ncbi.nlm.nih.gov/pubmed/24089451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316032110
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