Kindlin-2 controls bidirectional signaling of integrins

Control of integrin activation is required for cell adhesion and ligand-induced signaling. Here we report that loss of the focal adhesion protein Kindlin-2 in mice results in peri-implantation lethality caused by severe detachment of the endoderm and epiblast from the basement membrane. We found tha...

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Bibliographic Details
Main Authors: Montanez, Eloi, Ussar, Siegfried, Schifferer, Martina, Bösl, Michael, Zent, Roy, Moser, Markus, Fässler, Reinhard
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2008
Subjects:
Research Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377186/
https://ncbi.nlm.nih.gov/pubmed/18483218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.469408
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