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Kindlin-2 controls bidirectional signaling of integrins
Control of integrin activation is required for cell adhesion and ligand-induced signaling. Here we report that loss of the focal adhesion protein Kindlin-2 in mice results in peri-implantation lethality caused by severe detachment of the endoderm and epiblast from the basement membrane. We found tha...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2377186/ https://ncbi.nlm.nih.gov/pubmed/18483218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.469408 |
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