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Kindlin-3 regulates integrin activation and adhesion reinforcement of effector T cells
Activated T cells use very late antigen-4/α4β1 integrin for capture, rolling on, and firm adhesion to endothelial cells, and use leukocyte function-associated antigen-1/αLβ2 integrin for subsequent crawling and extravasation. Inhibition of α4β1 is sufficient to prevent extravasation of activated T c...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3801036/ https://ncbi.nlm.nih.gov/pubmed/24089451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316032110 |
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