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Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus
The role of integrin-mediated adhesion during T cell progenitor homing to and differentiation within the thymus is ill-defined, mainly due to functional overlap. To circumvent compensation, we disrupted the hematopoietic integrin regulator kindlin-3 in mice and found a progressive thymus atrophy tha...
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| Опубликовано в: : | eLife |
|---|---|
| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
eLife Sciences Publications, Ltd
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6126919/ https://ncbi.nlm.nih.gov/pubmed/30187863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35816 |
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