Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3

BACKGROUND AND PURPOSE: Aberrant activation of STAT3 is frequently encountered and promotes proliferation, survival, metastasis and angiogenesis in hepatocellular carcinoma (HCC). Here, we have investigated whether emodin mediates its effect through interference with the STAT3 activation pathway in...

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Bibliografske podrobnosti
Main Authors: Subramaniam, Aruljothi, Shanmugam, Muthu K, Ong, Tina H, Li, Feng, Perumal, Ekambaram, Chen, Luxi, Vali, Shireen, Abbasi, Taher, Kapoor, Shweta, Ahn, Kwang Seok, Kumar, Alan Prem, Hui, Kam M, Sethi, Gautam
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2013
Teme:
Research Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799595/
https://ncbi.nlm.nih.gov/pubmed/23848338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12302
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