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γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model

Angiogenesis is one of the key hallmarks of cancer. In this study, we investigated whether γ-tocotrienol can abrogate angiogenesis-mediated tumor growth in hepatocellular carcinoma (HCC) and if so, through what molecular mechanisms. We observed that γ-tocotrienol inhibited vascular endothelial growt...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Siveen, Kodappully Sivaraman, Ahn, Kwang Seok, Ong, Tina H., Shanmugam, Muthu K., Li, Feng, Yap, Wei Ney, Kumar, Alan Prem, Fong, Chee Wai, Tergaonkar, Vinay, Hui, Kam M., Sethi, Gautam
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Impact Journals LLC 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039111/
https://ncbi.nlm.nih.gov/pubmed/24722367
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