Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3

BACKGROUND AND PURPOSE: Aberrant activation of STAT3 is frequently encountered and promotes proliferation, survival, metastasis and angiogenesis in hepatocellular carcinoma (HCC). Here, we have investigated whether emodin mediates its effect through interference with the STAT3 activation pathway in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Subramaniam, Aruljothi, Shanmugam, Muthu K, Ong, Tina H, Li, Feng, Perumal, Ekambaram, Chen, Luxi, Vali, Shireen, Abbasi, Taher, Kapoor, Shweta, Ahn, Kwang Seok, Kumar, Alan Prem, Hui, Kam M, Sethi, Gautam
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Publishing Ltd 2013
Aiheet:
Research Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799595/
https://ncbi.nlm.nih.gov/pubmed/23848338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12302
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