Transcription activator like effector (TALE)-directed piggyBac transposition in human cells

Insertional therapies have shown great potential for combating genetic disease and safer methods would undoubtedly broaden the variety of possible illness that can be treated. A major challenge that remains is reducing the risk of insertional mutagenesis due to random insertion by both viral and non...

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Главные авторы: Owens, Jesse B., Mauro, Damiano, Stoytchev, Ilko, Bhakta, Mital S., Kim, Moon-Soo, Segal, David J., Moisyadi, Stefan
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2013
Предметы:
Synthetic Biology and Chemistry
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799441/
https://ncbi.nlm.nih.gov/pubmed/23921635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt677
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