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RNA-guided piggyBac transposition in human cells

Safer and more efficient methods for directing therapeutic genes to specific sequences could increase the repertoire of treatable conditions. Many current approaches act passively, first initiating a double-stranded break, then relying on host repair to uptake donor DNA. Alternatively, we delivered...

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Bibliografiska uppgifter
I publikationen:Synth Biol (Oxf)
Huvudupphovsmän: Hew, Brian E, Sato, Ryuei, Mauro, Damiano, Stoytchev, Ilko, Owens, Jesse B
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642342/
https://ncbi.nlm.nih.gov/pubmed/31355344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/synbio/ysz018
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