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Chimeric piggyBac transposases for genomic targeting in human cells
Integrating vectors such as viruses and transposons insert transgenes semi-randomly and can potentially disrupt or deregulate genes. For these techniques to be of therapeutic value, a method for controlling the precise location of insertion is required. The piggyBac (PB) transposase is an efficient...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413120/ https://ncbi.nlm.nih.gov/pubmed/22492708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks309 |
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