Transcription activator like effector (TALE)-directed piggyBac transposition in human cells

Insertional therapies have shown great potential for combating genetic disease and safer methods would undoubtedly broaden the variety of possible illness that can be treated. A major challenge that remains is reducing the risk of insertional mutagenesis due to random insertion by both viral and non...

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Bibliografiske detaljer
Main Authors: Owens, Jesse B., Mauro, Damiano, Stoytchev, Ilko, Bhakta, Mital S., Kim, Moon-Soo, Segal, David J., Moisyadi, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Synthetic Biology and Chemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799441/
https://ncbi.nlm.nih.gov/pubmed/23921635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt677
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