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Rapamycin inhibition of mTORC1 reverses lithium-induced proliferation of renal collecting duct cells
Nephrogenic diabetes insipidus (NDI) is the most common renal side effect in patients undergoing lithium therapy for bipolar affective disorders. Approximately 2 million US patients take lithium of whom ∼50% will have altered renal function and develop NDI (2, 37). Lithium-induced NDI is a defect in...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3798728/ https://ncbi.nlm.nih.gov/pubmed/23884148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00153.2013 |
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