Activation of mTORC1 in Collecting Ducts Causes Hyperkalemia

Mutation of TSC (encoding tuberous sclerosis complex protein) and activation of mammalian target of rapamycin (mTOR) have been implicated in the pathogenesis of several renal diseases, such as diabetic nephropathy and polycystic kidney disease. However, the role of mTOR in renal potassium excretion...

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Autores principales: Chen, Zhenguo, Dong, Heling, Jia, Chunhong, Song, Qiancheng, Chen, Juan, Zhang, Yue, Lai, Pinglin, Fan, Xiaorong, Zhou, Xuan, Liu, Miao, Lin, Jun, Yang, Cuilan, Li, Ming, Gao, Tianming, Bai, Xiaochun
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2014
Materias:
Basic Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935580/
https://ncbi.nlm.nih.gov/pubmed/24203997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013030225
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