The Deviant ATP-binding Site of the Multidrug Efflux Pump Pdr5 Plays an Active Role in the Transport Cycle

Pdr5 is the founding member of a large subfamily of evolutionarily distinct, clinically important fungal ABC transporters containing a characteristic, deviant ATP-binding site with altered Walker A, Walker B, Signature (C-loop), and Q-loop residues. In contrast to these motifs, the D-loops of the tw...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Furman, Christopher, Mehla, Jitender, Ananthaswamy, Neeti, Arya, Nidhi, Kulesh, Bridget, Kovach, Ildiko, Ambudkar, Suresh V., Golin, John
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Membrane Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798506/
https://ncbi.nlm.nih.gov/pubmed/24019526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.494682
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares