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Diminished origin licensing capacity specifically sensitises tumour cells to replication stress
Previous studies have shown that dormant licensed replication origins can be exploited to enhance recovery from replication stress. Since tumour cells express high levels of origin licensing proteins, we examined whether depletion of such factors might specifically sensitise tumour versus non-tumour...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3797919/ https://ncbi.nlm.nih.gov/pubmed/23364533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0491 |
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